Galectin-3 Level in Liver Injured Rats Treated with Nigella sativa and Honey Mixture
Mahmoud Abdel Halim Abdel Monem Sayed;
Abstract
The current study was carried out to investigate the potential inhibitory effect of Nigella sativa (black seed) and honey, as mixture and separately, on galectin-3 level in thioacetamide induced liver fibrosis in rats. Both of Nigella sativa and honey are well known for their medicinal properties especially their hepatoprotective and anti-fibrotic properties against various hepatotoxins.
Galectin-3 (Gal-3) is β-galactoside binding lectin that appeared recently to have primary role in TGF-β1 induced fibrogenesis. Galectin-3 expression was found to increase during liver induced injury and propagation of fibrosis, as well as galectin-3 gene knockout attenuates fibrogenesis progression in experimental liver fibrosis models. Because of their hepatoprotective and anti-fibrotic properties, Nigella sativa and honey are probable candidates to have inhibitory
Galectin-3 (Gal-3) is β-galactoside binding lectin that appeared recently to have primary role in TGF-β1 induced fibrogenesis. Galectin-3 expression was found to increase during liver induced injury and propagation of fibrosis, as well as galectin-3 gene knockout attenuates fibrogenesis progression in experimental liver fibrosis models. Because of their hepatoprotective and anti-fibrotic properties, Nigella sativa and honey are probable candidates to have inhibitory
Other data
| Title | Galectin-3 Level in Liver Injured Rats Treated with Nigella sativa and Honey Mixture | Other Titles | مستوى جالكتين-3 فى الجرذان المصابة فى الكبد والمعاملة بخليط حبة البركة والعسل | Authors | Mahmoud Abdel Halim Abdel Monem Sayed | Issue Date | 2017 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.