Dermoscopy of Squamous Cell Carcinoma

Abstract

Abstract Purpose: The purpose of this study was to compare the dermoscopic features of well differentiated with moderately differentiated squamous cell carcinoma. Materials and Methods: An observational cross sectional design of 16 cases that assigned according to histopathologically analysis into two differentiated grades (well and moderately differentiated tumors). Then the polarized non-contact mode of a Dermlite© DL3 “Gen, USA” at a magnification of 10 × was used to capture dermoscopic images for both histopathological grades. The surface morphology and the dermoscopic criteria were recorded directly from the patients and included: the percentage of scales/keratin, white circles, white halos, white structurless areas, the presence of dotted, hairpin, glomerular, comma, linear irregular and arborizing vessels and their arrangement and pattern Results: Statistical analysis revealed that noduloulcerative and nodular surface morphology was associated to well differentiated SCC. As well as the presence of a central and diffuse distribution of scales/keratin were characterized to well differentiated tumour while the presence of a patchy distribution of scales/keratin and the bleeding were represented to moderate differentiated tumour and there no significant differences in others dermoscopic criteria. Conclusion: Dermoscopy may be regarded to be a reliable preoperative tool to distinguish well from moderately differentiated SCC, providing information that may be particularly useful for the management decisions of clinicians.