Neurocognitive Assessment in Patients with idiopathic epilepsy

Abstract

In the present study we have evaluated 30 patients with idiopathic epilepsy who were regularly attending the Pediatric neurology clinic, Ain Shams University, with male to female ratio 1:2 in whom 63% were using levetriacetam, while 33% were using valoproate 20% were using carbamazebine,6% using lamotrigine and 23% using poly therapy. They were compared to 30 healthy individuals of same age and sex groups who served as the control group. Fifty six % of patients had GTC seizures, 34% had absence seizures and 10% had focal seizures. The mean age of the studied patients was 10.72 years and the mean duration of treatment was 2.6years. As regards Wechsler Intelligence Scale for Children our study shows 26.7% of cases were very low mental function as regards total IQ, 30% low average, while 43% were average total IQ compared to 60% of controls were average total IQ while 26.7% were high average and 13.3% were very high. In our study, patient group had significantly lower full-scale (89.56±11.39), performance (89.56 ±12.53), and verbal IQs (91.44 ±10.82) compared with the control group (107.48±8.89, 1+50+5+7.56±9.45, 107.36±8.22 respectively).