Role of Vitamin D Supplementation in Immuno-modulation and Improvement of Symptoms of Patients with Chronic Spontaneous Urticaria

Abstract

CSU is allergic disease with more than 6 weeks continuous symptoms, this disease was considered as an auto-immune disease, results in allergic wheal formations and angioedema. Vitamin D at optimal levels plays an important role in adjusting innate immunity. People who has deficient or insufficient levels of serum vitamin D suffer from disturbance in immune system , so studies has been established to link between vitamin D and CSU , these studies try to assess the role of vitamin D administration in cases suffering from CSU , beside measuring serum vitamin D in these cases. This single blind randomized prospective study conducted to 50 patients with CSU, admitted to Ain shams hospital, 50 patients were divided into 2 groups according