The Hypothyroxinemia of Prematurity I' When and How to Treat?!
Enas Abd Allah Ali Abd Allah;
Abstract
Anatomic development of the hypothalamic-pituitary
thyroid system occurs during the first trimester of gestation.
The placenta is freely permeable to iodide but it imposes a relative barrier to the thyroid hormones and is impermeable to TSH.
The ontogeny of mature thyroid function involves
both hypothalamic pituitary thyroid gland ontogenesis and maturation as well as the maturation of each of the component systems for thyroid hormone action.
Hypothyroxinemia of prematurity means low levels of bound and free plasma concentrations ofT4 and T3 in the preterm infants.
Hypothyroxinemia of prematurity IS caused by a
combination of factors such as immaturity ofhypothalmo pituitary-thyroid axis, sudden loss of materno-fetal transfer ofT4 and effects of neonatal disease (non thyroidal illness).
thyroid system occurs during the first trimester of gestation.
The placenta is freely permeable to iodide but it imposes a relative barrier to the thyroid hormones and is impermeable to TSH.
The ontogeny of mature thyroid function involves
both hypothalamic pituitary thyroid gland ontogenesis and maturation as well as the maturation of each of the component systems for thyroid hormone action.
Hypothyroxinemia of prematurity means low levels of bound and free plasma concentrations ofT4 and T3 in the preterm infants.
Hypothyroxinemia of prematurity IS caused by a
combination of factors such as immaturity ofhypothalmo pituitary-thyroid axis, sudden loss of materno-fetal transfer ofT4 and effects of neonatal disease (non thyroidal illness).
Other data
| Title | The Hypothyroxinemia of Prematurity I' When and How to Treat?! | Other Titles | نقص هرمون الغدة الدرقية فى الاطفال ناقصى النمو متى وكيفية العلاج | Authors | Enas Abd Allah Ali Abd Allah | Issue Date | 2005 |
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