Comparative study between Degradable Bioglass and Hard tissue replacement as bone substitute inclusion of surgical bone defects

Abstract

This experimental study aimed at histological comparison between two bone substitute materials (Bioglass and HTR).

Eighteen healthy male New Zealand rabbits, each weighing froni 1.5 - 2 kg were used in this study. They were divided into three equal groups, each group contained six animals.

The animals were generally anaesthetized and prepared for creation of bilateral bone defects in calvarial bone (about 1.5 em diameter) using a trephine bur.

In the first group, the right defect was filled with HTR while the left defect was filled with Bioglass. In the second group the right defect was filled with HTR material while the left defect was left without any bone substitute (act as control side). In the third group the right defect was filled with Bioglass material while the left defect was left without any bone substitute (act as control side).