The Relation between Multidrug Resistance Gene (MDR1) Polymorphism and Response to tyrosine kinase inhibitors (TKIs) in Patients with Chronic Myeloid Leukemia (CML)
Hend Nabil Ahmed Ellithy;
Abstract
P-glycoprotein (Pgp) is a transmembrane protein that mediates multidrug resistance in multiple neoplasias, through regulation of the efflux of different chemotherapeutic agents (Arceci 1993).
Pgp is an Imatinib efflux, may result in suboptimal Imatinib b
Pgp is an Imatinib efflux, may result in suboptimal Imatinib b
Other data
| Title | The Relation between Multidrug Resistance Gene (MDR1) Polymorphism and Response to tyrosine kinase inhibitors (TKIs) in Patients with Chronic Myeloid Leukemia (CML) | Other Titles | العلاقه بين التغيرات الشكليه لجين مقاومة الدواء و الاستجابه للعلاج بالعقارات المانعه للتيروسين كيناس في مرض لوكيميا الدم الميلوديه المزمنه | Authors | Hend Nabil Ahmed Ellithy | Keywords | The Relation between Multidrug Resistance Gene (MDR1) Polymorphism and Response to tyrosine kinase inhibitors (TKIs) in Patients with Chronic Myeloid Leukemia (CML) | Issue Date | 2014 | Description | P-glycoprotein (Pgp) is a transmembrane protein that mediates multidrug resistance in multiple neoplasias, through regulation of the efflux of different chemotherapeutic agents (Arceci 1993). Pgp is an Imatinib efflux, may result in suboptimal Imatinib b |
Attached Files
| File | Size | Format | |
|---|---|---|---|
| 119862R9197.pdf | 746.57 kB | Adobe PDF | View/Open |
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.