The Relationship Between Low Serum Ferritin And Serum Zinc With Depressive Symptoms In Children
Amira Mohamed Dabour;
Abstract
Nutritional depression is among the commonest psychological disorders, the patients affected by low serum ferritin and/or low serum zinc show many mood and behavioral signs and symptoms of depressed individuals.
Aim of work
This study aims to correlate between the low serum ferritin and serum zinc, and the development of depressive symptoms.
Subjects and methods
The study was divided into
1)Subjects:
-Study group: fifty Children were selected from the outpatient clinic of National Nutritional Institute and Special Needs Center, Institute of Childhood Studies, Ain Shams University, with depression score ≥20.
-Control: group: 30 children with depression score <20.
Inclusion criteria:
-Children aged from 7-12 years
Exclusion criteria:
-Children with congenital anomalies.
-Children with other chronic diseases.
2) Methods:
A-Full history taking:
1) Personal history (name, age, gender)
2) Past history (operations, medications)
3) Family history
B-thorough medical examination of children & examine skin color of nails and lips
C-Anthropometric examination (height, weight, BMI)
D- Laboratory tests: Hb, MCV, MCH, MCHC, RDW, serum ferritin (by ELISA) and serum zinc.
E- A questionnaire will be filled in by each participant for the diagnosis of depression to be made. Using Arabic children depression inventory: (ACDI)
- The Child Depression Inventory (CDI) is a symptom-oriented instrument for assessing depression in children between the ages of seven and 17 years
-It is Designed to make quantitative measurements of the following symptoms of depression: mood disturbances; capacity for enjoyment; depressed self-evaluation; disturbances in behavior toward other people; and vegetative symptoms, which include fatigue, oversleeping, having difficulty with activities requiring effort, and other symptoms of passivity or inactivity
-The inventory consists of 27-items each item assesses 1 symptom by presenting 3 choices ranging from 0–2 in the direction of increasing psychopathology and total score ranges from 0–54. Those who scored ≥ 20 were considered as having mild depressive symptoms.
A sample of blood obtained by a venous blood draw in the lab to assess serum level of ferritin and zinc.
Aim of work
This study aims to correlate between the low serum ferritin and serum zinc, and the development of depressive symptoms.
Subjects and methods
The study was divided into
1)Subjects:
-Study group: fifty Children were selected from the outpatient clinic of National Nutritional Institute and Special Needs Center, Institute of Childhood Studies, Ain Shams University, with depression score ≥20.
-Control: group: 30 children with depression score <20.
Inclusion criteria:
-Children aged from 7-12 years
Exclusion criteria:
-Children with congenital anomalies.
-Children with other chronic diseases.
2) Methods:
A-Full history taking:
1) Personal history (name, age, gender)
2) Past history (operations, medications)
3) Family history
B-thorough medical examination of children & examine skin color of nails and lips
C-Anthropometric examination (height, weight, BMI)
D- Laboratory tests: Hb, MCV, MCH, MCHC, RDW, serum ferritin (by ELISA) and serum zinc.
E- A questionnaire will be filled in by each participant for the diagnosis of depression to be made. Using Arabic children depression inventory: (ACDI)
- The Child Depression Inventory (CDI) is a symptom-oriented instrument for assessing depression in children between the ages of seven and 17 years
-It is Designed to make quantitative measurements of the following symptoms of depression: mood disturbances; capacity for enjoyment; depressed self-evaluation; disturbances in behavior toward other people; and vegetative symptoms, which include fatigue, oversleeping, having difficulty with activities requiring effort, and other symptoms of passivity or inactivity
-The inventory consists of 27-items each item assesses 1 symptom by presenting 3 choices ranging from 0–2 in the direction of increasing psychopathology and total score ranges from 0–54. Those who scored ≥ 20 were considered as having mild depressive symptoms.
A sample of blood obtained by a venous blood draw in the lab to assess serum level of ferritin and zinc.
Other data
| Title | The Relationship Between Low Serum Ferritin And Serum Zinc With Depressive Symptoms In Children | Other Titles | علاقة نقص الفريتيين والزنك في ظهور أعراض الاكتئاب عند الأطفال | Authors | Amira Mohamed Dabour | Issue Date | 2014 |
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