Phytochemical and Biological Studies on Reseda muricata

Abstract

This work has been carried out to investigate Reseda muricata at its natural habitats in the Egyptian desert especially at K 140 in Dahab - Sharm El-Sheikh road and K 25 Noweibaa -Taba road. The phytochemical studies comprised investigation of sugars, amino acids, lipids and flavonoids. The remarkable phytochemical results are the presence of a new flavonoid trioside [Kaempferol -3-0- -D- glucosyl-(1"'---+2")-0-a-L-rhamn- oside -7-0- -D­ glucoside ] together with its coumarylester [Kaempferol -3-0- -D- glucosyl­ (1'"---+2") -0-a-L-rhamnoside-7-0- -D-(6""-0-E-coumaryl-glucoside)], beside 7 known flavonoids and 5 phenolic acids. By Making pharmacological and biochemical screening to the effect of 6 different plant extracts. It was found that the plant extracts have anti­ inflammatory,' analgesic and diuretic activities beside the absence of any obvious significant ulcerogenic effect. The biochemical studies revealed that the plant extracts is not only safe on RBCs, WBCs, Hb%, kidney function, liver function but also they decrease triglycerides, cholesterol, LDL and body weight, especially by flavonoids and diethylether extracts. Reseda muricata extracts in different concentrations showed significant decrease in the growth rate of some bacteria, fungi and yeast especially by the ethyl acetate extract.