Impact of Vitamin D Deficiency on Severity and Control of Bronchial Asthma in Children
Mohamed Haggag Hassan Hassan;
Abstract
A
sthma is a common disease, affecting an estimated 300 million individuals worldwide, and has a significant social and financial burden on the individuals and families affected. Factors such as genetic predisposition, early allergen exposure, infections, diet, tobacco smoke exposure, pollution, and vitamin D status are all proposed to influence the development and severity of asthma.
Vitamin D deficiency and insufficiency are increasingly being recognized in the general population, and have been largely attributed to lifestyle changes over the last few decades. There is growing appreciation of the likely importance of vitamin D as a pleiotropic mediator that contributes to pulmonary health. Epidemiologic data suggest that low serum vitamin D in children with asthma is associated with more severe disease.
The present study was conducted on 90 persistent asthmatic children with average age 2-18 years, with or without other form of allergy who were enrolled from the Pediatric Allergy and Immunology Unit, Children's Hospital, Ain Shams University. We aimed to investigate the relationship between serum 25 (OH)vitamin D level and the grade of asthma severity and degree of its control
sthma is a common disease, affecting an estimated 300 million individuals worldwide, and has a significant social and financial burden on the individuals and families affected. Factors such as genetic predisposition, early allergen exposure, infections, diet, tobacco smoke exposure, pollution, and vitamin D status are all proposed to influence the development and severity of asthma.
Vitamin D deficiency and insufficiency are increasingly being recognized in the general population, and have been largely attributed to lifestyle changes over the last few decades. There is growing appreciation of the likely importance of vitamin D as a pleiotropic mediator that contributes to pulmonary health. Epidemiologic data suggest that low serum vitamin D in children with asthma is associated with more severe disease.
The present study was conducted on 90 persistent asthmatic children with average age 2-18 years, with or without other form of allergy who were enrolled from the Pediatric Allergy and Immunology Unit, Children's Hospital, Ain Shams University. We aimed to investigate the relationship between serum 25 (OH)vitamin D level and the grade of asthma severity and degree of its control
Other data
| Title | Impact of Vitamin D Deficiency on Severity and Control of Bronchial Asthma in Children | Other Titles | دراسة تأثير نقص فيتامين د على شدة مرض الربو الشعبى لدى الأطفال | Authors | Mohamed Haggag Hassan Hassan | Issue Date | 2015 |
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