Changes In Adipocyte Hormones In Relation To Body Composition And Pubertal Development In Obese Adolescents After Physical Activity And Dietary- Restriction Programs.

Abstract

Obesity in children and adolescents is a global public health concern and is associated with a range of short- and long-term health complications . It increased rapidly all over the world and affecting virtually both developed and developing countries of all socioeconomic groups including all age groups thereby posing an alarming problem, described by the World Health Organization (WHO) as an “escalating global epidemic.” An association between plasma Adiponectin and plasma leptin concentrations with body composition had been describd in obese adolescents, finding from recent reports suggested that Intervention with structured exercise and diet program can play an important role in improving the level of these hormones and the health for obese children. The aim of this work is to identify the factors that affect the body composition in obese adolescents through identification of the role of adiponectin and leptin hormones (after physical activity and dietary restriction program for six month) to modulate the role of these hormones. In order to achieve these objectives, this work was conducted on sixty adolescents suffering from obesity, based on their body mass index; which is greater than the 95th percentile for age and gender based Egyptian Growth Reference Charts. Studieded obese adolescents subdivided into two groups: Group A:30 obese adolescents. The mean age were 13.2 ± 0.9years 53%males ,46.7 females were subjected to exercise and nutrition program ,Group B:30 obese adolescents The mean age were 13.1 ± 0.9years 50%males ,50% females were subjected to diet program only . Both groups A&B were collected from Nutritional clinic at the National Research Center were included in the study . . All obese adolescents under went physical activity and dietary restriction program were subjected to the following before and after 6 months of the program :full medical history taking, anthropometric measurements ,body composition analysis , thorough clinical examination,lipid profile and hormonal assessment.