ntroduction: Cervical cancer is considered the third most common gynecological malignancy in women. Although patient now survive longer due to radiation therapy and more effective chemotherapy, it remains the most frequent cause of death for women in developing countries. Aim of the Work: To highlight the role of magnetic resonance spectroscopy in the diagnosis of uterine cancer cervix. Methodology: Cervical cancer is both the fourth most common cause of cancer and the fourth most common cause of death from cancer in women and in Egypt Cervical cancer ranks as the second most frequent cancer among women. Functional MRI is becoming established in the evaluation of gynecologic malignancies including uterine cervical malignancies. Parameters derived from functional MRI may be used toexamine tumor vascularity Tissue micro architecture, hypoxic status and metabolic profile features that may be Exploited for tumor characterization , staging and response to treatment. Conclusion: MRS has lower sensitivities and requires much longer acquisition times and more complex data processing, and with clinicians unfamiliar with the technique, these factors continue to limit the application of MRS in the clinical setting. Currently, there are methodologies that optimize the combined signals from multi element coil arrays to improve detection of low concentration metabolites in MRS. And, in order to improve its sensitivity and spectral resolution. In addition, the availability of higher field strength MR systems can reduce some of these limitations. Keywords: Role of MR Spectroscopy, Diagnosis of Uterine Cervical Cancer

Abstract

Introduction: Cervical cancer is considered the third most common gynecological malignancy in women. Although patient now survive longer due to radiation therapy and more effective chemotherapy, it remains the most frequent cause of death for women in developing countries. Aim of the Work: To highlight the role of magnetic resonance spectroscopy in the diagnosis of uterine cancer cervix. Methodology: Cervical cancer is both the fourth most common cause of cancer and the fourth most common cause of death from cancer in women and in Egypt Cervical cancer ranks as the second most frequent cancer among women. Functional MRI is becoming established in the evaluation of gynecologic malignancies including uterine cervical malignancies. Parameters derived from functional MRI may be used toexamine tumor vascularity Tissue micro architecture, hypoxic status and metabolic profile features that may be Exploited for tumor characterization , staging and response to treatment. Conclusion: MRS has lower sensitivities and requires much longer acquisition times and more complex data processing, and with clinicians unfamiliar with the technique, these factors continue to limit the application of MRS in the clinical setting. Currently, there are methodologies that optimize the combined signals from multi element coil arrays to improve detection of low concentration metabolites in MRS. And, in order to improve its sensitivity and spectral resolution. In addition, the availability of higher field strength MR systems can reduce some of these limitations. Keywords: Role of MR Spectroscopy, Diagnosis of Uterine Cervical Cancer