Recent Update of cannabinoids effect on the body

Abstract

spread use in different forms.the most common route of administration is in a water pipe followed by smoking in cigarettes. Nearly 93% smoke the flowering heads of the plant. Also, others use cannabis by means of chewing or sometimes mixed with other psychoactive drugs. Another method is a beverage, which is made from an infusion of cannabis leaves and flowering tops combined with milk and nuts and is consumed through drinking. Herbal cannabis contains over 400 compounds including over 60 cannabinoids. The pharmacology of most of the cannabinoids is largely unknown but the most potent psychoactive agent, 9-tetrahydrocannabinol ( 9-THC, or THC), has been isolated, synthesized and much studied. Other plant cannabinoids include 8-THC, cannabinol and cannabidiol. These and other cannabinoids have additive, synergistic or antagonistic effects with THC and may modify its actions when herbal cannabis is smoked. Synthetic cannabinoids such as nabilone and others are also available for therapeutic and research purposes. The latter half of the twentieth century witnessed a dramatic increase in the availability and use of cannabis throughout world. Summary 157 In 1991, it was declared that cannabis is the most widely used substance