Increased Expression of Matrix Metalloproteinase-9 in the Ectopic Endometrial Tissue of Women with Endometriosis Prospective study

Abstract

Endometriosis is a common gynecological disorder affecting about ten to fifteen percent of women in the reproductive age and up to 50% of infertile patients are affected by endometriosis. The disease is characterized by the ectopic location of endometrial cells in tissues other than the uterine cavity its main symptoms are chronic pelvic pain, dyspareunia, and infertility

MMPs form a multigenic family of proteolytic enzymes thatdepend on zinc for activation Aim of the work:

The aim of the present study is to evaluate MMP-9 forms in the ectopic and eutopic endometrial tissue of women with endometriosis Conclusion: We conclude that Matrix Metalloproteinase-9(MMPs-9) is increased in the cases of endometriosis that prove that mmp9 is a good marker for endometriosis Key words:

Endometriosis , matrix metalloproteinase-9