Anesthetic management of the Pediatric patient with Neuromuscular Disease

Abstract

The neuromuscular disorders are a heterogeneous group of diseases effecting skeletal muscle via abnormalities of the motor nerves, NMJ, cellular matrix, ion channels and metabolic derangements. They are often grouped together in relation to anaesthesia due to common considerations in the perioperative period. However, it is important to remember that each disease state has its own distinct pathophysiology that requires individually tailored perioperative care. An understanding of these disorders is especially helpful in paediatrics where the first presentation of a subclinical myopathy may be under general anaesthesia.(Sarah M et al., 2011)