VALUE OF SERUM ESTRADIOL LEVEL ESTIMATION ON THE DAY OF HCG ADMINISTRATION ININTRACYTOPLASMIC SPERM INJECTION CYCLE

Abstract

SUMMARY I ntracytoplasmicsperm injection (ICSI) involves micro-manipulation techniques to inject a viable sperm into the ooplasm of the egg, after cumulus and corona cell removal (denudation), oocytes are used for microinjection. Since the birth of Louise Brown in July 1978, IVF has proven to be an efficient treatment to alleviate female factor infertility, especially tubal infertility. In subsequent years IVF was also successfully applied in couples with unexplained infertility, with male infertility as well as endometriosis. Since the second half of 1992, only ICSI has been applied in centers when assisted fertilization was indicated. ICSI is indicated in any infertile couple in whom there is a significant chance of failed or very poor fertilization following treatment with conventional IVF. Such couples include those with a previous history of a similar event. A group of patients who will benefit from having ICSI at the outset rather than conventional IVF are those who have a marked depression of their semen parameters. This includes patients with moderate to severe oligo-, astheno-, and/or teratozoospermia. The aim of this study was to assess the relation between serum E2 level on the day of HCG administration and ICSI outcome.