Development of sensitive HPLC method with fluorescence detection for determination of memantine and its application to pharmacokinetic study

Mohamed Gamaleldin Hassan Oraby;

Abstract


A sensitive HPLC method with FL detection for measuring MT in pure was developed. The method was based on labeling of MT with DIB-Cl reagent at 45°C for 35 min to yield the fluorescent DIB-MT and measuring the RFI at 440 nm after excitation at 330 nm. By


Other data

Title Development of sensitive HPLC method with fluorescence detection for determination of memantine and its application to pharmacokinetic study
Other Titles تطوير طريقه حساساه بكروهاتوجرافيه السائل عالى الكفاءه بالكشف اللصفى لتعيين الميمانتين وتطبيقاتها لدراسة حركيه الدواء
Authors Mohamed Gamaleldin Hassan Oraby
Keywords Development of sensitive HPLC method with fluorescence detection for determination of memantine and its application to pharmacokinetic study
Issue Date 2013
Description 
A sensitive HPLC method with FL detection for measuring MT in pure was developed. The method was based on labeling of MT with DIB-Cl reagent at 45°C for 35 min to yield the fluorescent DIB-MT and measuring the RFI at 440 nm after excitation at 330 nm. By

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