THERAPEUTIC EFFECT OF LASER AND L-CARNITINE AGAINST AMIODARONE-INDUCED PULMONARY TOXICITY IN ADULT MALE RAT

Abstract

The present study is a trying to investigate the complications effect of amiodarone on some physiological parameters and histological studies on the lung tissue in adult male rats. The work also evaluates the therapeutic role of laser and L-carnitine to minimize hazardous effects of amiodarone which cause lung toxicity. Results were obtained from the treated experimental animal groups and compared with the corresponding normal control rat group. The present findings were further discussed in view of relevant available literature in similar fields of studies. The following parameters were estimated: - Antioxidants profile, enzymes of lung, oxidative stress & inflammatory status and cytochromes. Lung of albino rats was chosen for the histological studies to elucidate the impact of amiodarone on lung tissue and the ameliorating effects of Laser and L. carnitine. In the light of the obtained results, conclusions were deducted and suggestions for further studies were introduce