Ratio of Estrogen to Number of Follicles ≥14mm on Day of Trigger as a Prognostic Tool for In Vitro Fertilization Cycles

Abstract

Infertility is usually described as the inability of a couple to conceive after one year of unprotected intercourse (Griffin and Finch, 2005). Infertility is a major health problem affecting about 10-20% of couples (Mittal et al., 2004). Since infertility represents a major physiological and psychological problem to a growing proportion of the population, governments worldwide are investing heavily in assisted reproductive technology (ART) which has led to significant improvements in our understanding of male/female reproductive systems, gamete preservation and gamete manipulation (Cohen et al., 2005). The quality of oocytes and embryo quality are important determinants of the success of IVF. Serum estradiol as a factor affecting these parameters has been studied in only a few publications. Also, serum estradiol on the day of HCG as a factor in IVF success is controversial with both positive as well as negative relations quoted in the literature (Mittal et al., 2014). Our study conducted at Ain-Shams University El-Demerdash Hospital, IVF Center, from September 2016 till the end of the study population at June 2017. We studied 82 cases prospectively and our inclusion criteria included age will range from 20-40 years old and Sub fertile women undergoing long agonist protocol ICSI cycles and our exclusion criteria included sever male factor infertility and