Assessment of Sweat Constituents Quantitatively with Histopathological Changes in Patients with Recurrent Infection of Pityriasis Versicolor

Abstract

it. Versicolor is a widespread fungal skin disease which affects a high percentage of the population about 2-8% of the US population. It is higher in tropical and warm areas, so this percentage is more in Egypt population than in US population .It has been found that this type of fungus increases in proportion with fat, as well as with dead cells where used as raw materials in its growth and reproduction. It was found that it increases also with increasing cases of seborrheic dermatitis and increased secretions of sweat. Pit. Versicolor is described as oval irregular shaped scaly spots overall diameter ranges between (0.6 to 2.5 cm) and sometimes merge in shape to represent larger size. Skin ranges in color from pale pink to red and finally dark brown People with darker skin show hypo pigmented changes of the skin color, but hyperpigmentation remains the most common. Sometimes be accompanied by itching. Skin itching increases in warm places and subside after the beginning of the secretion of sweat. These patches are normally found in the back and underarms and arm, chest, legs and neck, and when examined microscope appear as spaghetti and meatballs. Pit. Versicolor Can be diagnosed by using potassium hydroxide (10-20%) solution. Woods light show orange color on the affected skin and thus can be distinguished from other diseases. The purpose of the study: Quantitative assay of the components in sweat with the changes in cases with repeated infection By Pit. Versicolor, as well as measuring the ph. and compared to the control group who never infected before By Pit. Versicolor, in addition to the histopathological changes with dermoscopic picture .The most appropriate therapeutic methods according to what has been reached from the results is also carried out in multiple modalities to study the correlation between infection, sweat constituents and most effective therapeutic modality. Cases and research methods: The study will include 90 calibers, divided into:  45 of them with recurrent Pit. Versicolor infections distributed on the back and arms. The average age group range between (18-35) years and all are males.  Other 45 calibers from the same age group, gender, and body mass indices never have the disease before as a comparison group. All will participate in the study will be su