Evaluation of some Predictors of the Outcome of Patients with Corrosive Ingestion in the Poison Control Center, Ain Shams University Hospitals (A Prospective study)

Abstract

Caustic ingestion continues to be a major health hazard in developed and developing countries. A large number of patients have mild post-corrosive injuries and most often recover without serious complications, but significant number of patients have severe chemical injuries and complications of the upper gastrointestinal tract and a high percentage of mortality. Prediction of the presence and severity of esophageal injury following ingestion of a caustic substance is a challenging problem. The use of initial symptoms and signs or laboratory tests to predict the outcome of esophageal injury is controversial. One study developed a new score known as DROOL Score, which is a new prognostic method based on initial symptoms and signs to predict stricture formation without endoscopic grading. The aim of this work was to study the value of the intoxication data, clinical findings and certain laboratory parameters in the early prediction of the outcome following corrosive ingestion, and test the applicability of DROOL Score as a prognostic indicator of esophageal stricture. The present study is a prospective cohort study performed on patients admitted to poison control center of Ain Shams University Hospital (PCCA) with history of corrosive ingestion during the period from the 1st of June 2015 to the 30th of November 2015. During the period of the present study the total number of patients with corrosive poisoning that presented to the emergency department were 1010, 92 patient were subjected in the current study,6 patients died.