The Relation Between Psychiatric Disorders and Substance Abuse in Adolescence and Young Adulthood

Abstract

OPD is a common preventable and treatable disease, is characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airway and lung to noxious particles or gases Worldwide, the most commonly encountered risk factor for COPD is tobacco smoking. Pulmonary hypertension (PH) is a progressive disorder characterized by abnormally elevated blood pressure of the pulmonary circulation that results, over time, from extensive vascular remodeling and increased pulmonary vascular resistance

Aim of Work:

Assess the role of Cardiac MRI in severe COPD patients with pulmonary artery pressure more than 35 mmHg as evaluated by Echocardiography and right sided cardiac catheterization .

Results:

(10) Among 20 COPD patients with PH, The mean age was 64.50 ± 7.94 with direct sig-nificant correlation between the age and mPAP between group A (mPAP between 35 and 43.5 mmHg) and group B (mPAP between 43.5 and 101 mmHg). The study showed male predomin-ance with 18 male patients and 2 female patients. (11) The studied 20 patients showed 9 patients with co-morbidities, 7 patients of them were in group B (mPAP between 43.5 and 101 mmHg), the co-morbidities included Morbid obesity, DVT , chronic kidney disease, hepatitis C virus and hyperlipidemia. (12) HRCT showed 12 patients with emphysema only and 8 patients with combined em-physema and ILD syndrome. The patients with combined emphysema and ILD syn-drome were more in group B (mPAP between 43.5 and 101 mmHg). (13) V/Q scan gave important results, with 4 positive CTEPH patients, all of them were in group B (mPAP between 43.5 and 101 mmHg). This show importance of considering other co-morbidities with higher mPAP.