New Synthetic Approaches For Azines And Their Fused Derivatives

Abstract

This work has been carried out to investigate the synthesis of new derivatives of 3-

cyanopyridine-2(1H)-thione containing cycloketones. The reactions of the latter compounds with halogenated compounds were stodied. The stodied halogenated compounds were a-chloroacetanilides, 3-bromoacetylcoumarin , 3-chloropentan-2,4- dione and y-bromoacetoacetanilide, The products of some foregoing reactions were used for synthesis of heterocycles e.g. pyrazole, isoxazole, pyridine and pyrimidine incorporated with cyanopyridine moiety. The structures of all compounds wer