RISK FACTORS OF CHILDHOOD LEUJ(EMIA (A Case-control study)

DALIA BILAL MOHAMMED


Abstract


Leukemia is the most •common cancer in .children. In the NCI, Cairo from 1990-1994 lymphohematopoietic malignancies :(leukemia 33.54% and lymphoma 30.45%) werethe commonest below age of 18 years. This cross sectional case control study was carried out to evaluate '\ different risk factors, and find association of many•possible risk factors ' for childhood leukemia as it may be possible'to begin to consider the \ feasibility of applying preventive 111easures or intervention strategies{or ) it. The study included I OOpediatric leukemic case from the NCI Cairo and 250 pediatric controls age and sex matched with cases, 150 siblings • fcases -(internal controls), and I 00 nonfamily{external •controls). \Univariate analysis showed that: birth order, ,paternal smoking and nun1t::er of cigarette/day, family history of •cancer and anomalies, preco c otion radiation and hormonal treatment of the mother for infertility,l,conti'aceptive drugs, pregnancy at extremes ofchildbearing period, exposure to radiation during pregnancy, drug intake during -pregnancy, e.onatal cyanosis, neonatal drug intake, lesser period of br ast feeding: -.,consanguinity and certain patemal occupation were associated with in'creased likelihood ofchildhood leukemia.


Other data

Other Titles العوامل المساعدة على حدوث سرطان الم فى الاطفال (دراسة لحالات وحالات ضابطة)
Issue Date 2001
URI http://research.asu.edu.eg/handle/12345678/25009


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