Contrast Enhanced Mammography In The Diagnosis Of Breast Cancer

Abstract

Though mammography widely established as the only screening imaging modality that can reduce breast cancer mortality, it has some limitations, such as lesions masked by normal fibroglandular tissue, lesions seen on only one view, and subtle architectural distortions. Partly because of these limitations, misses about 20% of invasive breast cancers. Also the accuracy of mammography is limited in dense breasts where surrounding fibroglandular tissue decreases the conspicuity of lesions. Even when tumors are detected, the full extent of disease may not be clearly depicted. CEDM is a relatively new imaging technique capable of detecting neo-angiogenesis and has the potential to play an important role in assessing multifocality or multicentricity in breast cancer, or even in screening the population of women with high-density breasts. CESM provides immediately available, clinically useful information in the symptomatic clinic in patients with suspicious palpable abnormalities. sensitivity, specificity, and size accuracy for breast cancer detection and staging are all improved using CESM as the primary mammographic investigation. Dual energy contrast enhanced mammography depicts lesions independent of size, depicting cancers as small as 4 mm. .Tumor size on Dual energy contrast enhanced mammography images is an accurate indicator of histologic size of the tumor.