Synthesis and Reactions of New Heterocyclic Compounds as Bases for Some Nucleosides with Expected Biological Activities

نجلاء سالم السيد ابراهيم;

Abstract


This work has been carried out to investigate the synthesis of some new nicotinonitrile derivatives, as well as, 5,6-dimethyl-4-(4-methoxy­ phenyl)pyrazolo[3,4-b]pyridin-3-amine, that was utilized as a good synthone for the preparation of different heterocyclic compounds, by its reaction with various electrophiles.
In addition, investigating the analgesic and anti-inflammatory
activities of some selected compounds.
Moreover, the preparation of some acyclic nucleosides and cyclic thioglycosides.


Other data

Title Synthesis and Reactions of New Heterocyclic Compounds as Bases for Some Nucleosides with Expected Biological Activities
Other Titles تحضير وتفاعل مركبات عضوية جديدة غير متجانسة الحلقة كقواعد لتحضير بعض النيوكلوسيدات والمتوقع لها نشاط بيولوجي
Authors نجلاء سالم السيد ابراهيم
Keywords : 2-oxo-1,2-dihydropyridine-3-carbonitrile , pyrazolo[3,4-b] pyridine derivatives, active methylene containing reagents, pyridopyrazolo­ pyrimidine, diazocoupling, glycosides, pharmacological activity.
Issue Date 2010

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