Catheter-Re¬lated and Infusion- Related Sepsis

Mohamed Fekry Abdel Latif Hewedy


About half of nosocomial bloodstream infections (BSIs) occur in intensive care units, and the majority are associated with the presence of an intravascular device. Catheter-related bloodstream infections (CR-BSI) are an important cause of morbidity and mortality worldwide, including resource-limited settings. All types of intravascular catheters pose significant but varying risk of infection. Duration of catheterization, catheter material, insertion conditions, and site care also impact the risk of catheter-associated infections. Bloodstream infection associated with central venous catheters can be attributed to four major sources: colonization from the skin, intraluminal or hub contamination, secondary seeding from a bloodstream infection, and contamination of the infusate In general, the diagnostic approach to catheter-related blood stream infection (CRBSI) consists of clinical evaluation and microbiologic confirmation with peripheral blood and catheter cultures. Catheter-related bloodstream infection (CRBSI) should be suspected when bloodstream infection occurs in the setting of a central venous catheter with no other apparent source. Fever is the most sensitive clinical manifestation. Other clinical manifestations include hemodynamic instability, altered

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Other Titles تعفن الدم الناتج عن القسطره وضخ السوائل الوريديه
Issue Date 2014

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