CLINICAL AND MICROBIOLOGICAL STUDIES ON THE USE OF MEDICINAL MAGGOTS IN THE MANAGEMENT OF DIABETIC FOOT ULCERS
Mohammed El-Sayed Mohammed El-Naggar;
Abstract
The aim of the present study was to investigate the clinical and antimicrobial efficacy of medicinal maggots of Lucilia sericata in the treatment of nonhealing diabetic foot ulcers unresponsive to conventional treatment and surgical intervention. In addition, antibiotic resistance patterns of the different bacterial isolates swabbed from ulcers before initiating maggot therapy have been investigated.
This maggot therapy study was conducted on a cohort of I 0 patients (3 males and 7 females) with 13 diabetic foot ulcers at the Vascular Surgery Unit of the Department of Surgery, Faculty of Medicine, University of Alexandria and the Diabetic Foot Unit of Alexandria Main University Hospital. The mean age of patients was
53.3 years (range 31-60 years). Twelve wounds were found to be infected, neuropathic ulcers and one wound was an infected, neuroischemic ulcer. No osteomyelitis has been detected in these ulcers. The ulcers had an initial mean surface area of 23.52 cm2 (range
1.32-63.13 cm2 ) and a mean age of 6.69 weeks (range 1-36 weeks).
Necrotic tissue represented a mean of 68.77% (range 29.97-100%) of the mean size of ulcers.
All the 13 ulcers examined were completely debrided by maggots during a mean period of 2.62 weeks (range 1-8 weeks) and through a mean of 2 cycles (range 1-4 cycles). Each cycle lasted 3
days. Maggots removed a mean of 6.l7cm 2 of necrotic tissue per
week. This represented a mean of 38.16% decrease in the size of
This maggot therapy study was conducted on a cohort of I 0 patients (3 males and 7 females) with 13 diabetic foot ulcers at the Vascular Surgery Unit of the Department of Surgery, Faculty of Medicine, University of Alexandria and the Diabetic Foot Unit of Alexandria Main University Hospital. The mean age of patients was
53.3 years (range 31-60 years). Twelve wounds were found to be infected, neuropathic ulcers and one wound was an infected, neuroischemic ulcer. No osteomyelitis has been detected in these ulcers. The ulcers had an initial mean surface area of 23.52 cm2 (range
1.32-63.13 cm2 ) and a mean age of 6.69 weeks (range 1-36 weeks).
Necrotic tissue represented a mean of 68.77% (range 29.97-100%) of the mean size of ulcers.
All the 13 ulcers examined were completely debrided by maggots during a mean period of 2.62 weeks (range 1-8 weeks) and through a mean of 2 cycles (range 1-4 cycles). Each cycle lasted 3
days. Maggots removed a mean of 6.l7cm 2 of necrotic tissue per
week. This represented a mean of 38.16% decrease in the size of
Other data
| Title | CLINICAL AND MICROBIOLOGICAL STUDIES ON THE USE OF MEDICINAL MAGGOTS IN THE MANAGEMENT OF DIABETIC FOOT ULCERS | Other Titles | دراسات اكلينيكية وميكروبيولوجية على استخدام يرقات الذباب الطبية فى علاج قرح القدم السكري | Authors | Mohammed El-Sayed Mohammed El-Naggar | Issue Date | 2005 |
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