ELECTROPHYSIOLOGICAL ASSESSMENT OF PHRENIC NERVE FUNCTION IN CHRONIC RENAL FAILURE CORRELATION WITH PULMONARY FUNCTIONS
Arwa M. Hosny El-Shafei;
Abstract
This study was conducted on twenty patients with chronic renal failure and ten normal subjects as a control group, of comparable sex and age. For the included subjects, ti.Jll history taking, full clinical examination, laboratory tests including blood levels of urea, serum creatinine, ionized serum calcium, phosphorus albumin and haemoglobin percent; chest X-ray, phremc nerve conduction studies and pulmonary function tests pre and post-bronchodilators were done.
It was found that there was elevated levels for blood urea, serum creatinine, i'onized serum calcium, and phosphorus and decreased values for serum albumin and haemoglobm percent, in the chronic renal failure patients compared with the control group
In patients group, revealed the presence of mild to moderate restrictive and mild maJor airways obstructive ventilatory dysfunction with moderate to severe small airway obstruction with statistically insignificant response to bronchodilators.
Phrenic nerve parameters revealed prolongation of the conduction time in the patients group compared to the control group.
I
The left phrenic nerve amplitude was found to be sensitive to changes in the ventilatory function as there was significant negative correlation between it and FEV 1 % and FEF5o%•
The right phrenic distal latency showed significant negative correlation with FEV 1%, FEV 1/FVC and FEF25_ 75 %.
From this study, we can conclude that FEV 1% is sensitive to affection of phrenic nerve in patients with chronic renal failure and affection of the phrenic nerve could be a factor in derangements of pulmonary functions encountered in chronic renal failure patie;1ts.
It was found that there was elevated levels for blood urea, serum creatinine, i'onized serum calcium, and phosphorus and decreased values for serum albumin and haemoglobm percent, in the chronic renal failure patients compared with the control group
In patients group, revealed the presence of mild to moderate restrictive and mild maJor airways obstructive ventilatory dysfunction with moderate to severe small airway obstruction with statistically insignificant response to bronchodilators.
Phrenic nerve parameters revealed prolongation of the conduction time in the patients group compared to the control group.
I
The left phrenic nerve amplitude was found to be sensitive to changes in the ventilatory function as there was significant negative correlation between it and FEV 1 % and FEF5o%•
The right phrenic distal latency showed significant negative correlation with FEV 1%, FEV 1/FVC and FEF25_ 75 %.
From this study, we can conclude that FEV 1% is sensitive to affection of phrenic nerve in patients with chronic renal failure and affection of the phrenic nerve could be a factor in derangements of pulmonary functions encountered in chronic renal failure patie;1ts.
Other data
| Title | ELECTROPHYSIOLOGICAL ASSESSMENT OF PHRENIC NERVE FUNCTION IN CHRONIC RENAL FAILURE CORRELATION WITH PULMONARY FUNCTIONS | Other Titles | تقييم الكهروفسيولوجية للعصب الحجابى فى مرضى الفشل الكلوى المزمن وعلاقتها بوظائف الرئة | Authors | Arwa M. Hosny El-Shafei | Keywords | .Diaphragm . Phrenic Nerve Neuropathy. Kidney. CRF Pulmonary Function, Pulmonary Complications in CRF Changes in Pulmonary Functions in CRF | Issue Date | 2002 |
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