A StudY on The Antloxldants In Leukaemlas and Sulid Malionant Tumours

Abstract

Our study included 78 patients of different ages and sexes with different hematological malignancies, 16 male patients with urinary bladder cancer and 15 female patients with breast cancer. They were all studied as regard the activity of erythrocyte GPX, SOD and GRX and were matched with control healthy subjects. Both GPX and SOD were found to be significantly decreased with significantly increase of GRX in most of hematological malignancies. There was a positive correlation between GPX and SOD in most of the studied groups. In contrast, breast cancer patients showed significantly increase of the activity of SOD, GPX and GRX when compared to the control group. On the other hand urinary bladder cancer patients showed only significant decrease of GPX activity in relation to the control subjects.