The Role of Serum Adiponectin Levels in Women with Polycystic Ovarian Syndrome: A Prospective Case-Control Study

Abstract

SUMMARY AND CONCLUSION I n conclusion, PCOS was found to correlate with low adiponectin levels, independently of BMI. Our study also confirmed the findings in a previous reports that the adiponectin is a marker of PCOS. The findings in this study also indicate that circulating adiponectin levels could be treated as a biomarker of insulin resistance and that the adipocytokine and metabolic biomarker levels are significantly correlated. The relationships between adiponectin and insulin resistance and sensitivity, metabolic syndrome, and BMI in women with PCOS suggest that adiponectin potentially could serve as a marker for disease risk and provide opportunity for earlier intervention if knowledge is successfully translated from laboratory to clinical practice. However, further study of the relationship between adiponectin and PCOS is required before there can be direct application to clinical practice.