Vaginal Misoprostol Before Intrauterine Contraceptive Device Insertion Following Previous Insertion Failure: Randomized Clinical Trial

Abstract

The intrauterine contraceptive device (IUCD) is a safe, extremely effective and long acting reversible contraceptive (LARC) method. It is possible that difficulty in inserting the device limits its use. Until a short time ago, the IUCD was indicated only for multiparas this recommendation probably originating from misgivings regarding a possible increase in the incidence of acute PID and the association between this condition and infertility. Although all subsequent studies have confirmed that this risk is low In an attempt to improve the ease of IUCD insertion. The current study tested the use of misoprostol prior to the insertion. Ninety women with a failed one attempt of IUCD insertion and candidate for T Cu 380A IUCD insertion participated in the study. Half of them were given 200 microgram of misoprostol vaginally and the other half was given the placebo (Vitamin C tablets). Key words: Cesarean Section- Molecular Weight- Pelvic inflammatory diseases- Postpartum hemorrhage- Partial thrombin time - Sexual transmitted diseases