SPLENIC AUTOTRANSPLANTATION (EXPERIMENTAL AND APPLIED STUDY

Abstract

his splenic

. • ' / f study included a total of 45 patients and 60 rabbits entered the

a6'totrans fantation program at the Gastroentrology Uhit,

Department of Gt;neral Surgery, Tanta l!niversity HospitaL

The present study included two parts, the first part was done on human beings'; and the second part was done on experimental animals! The first part of the study was done on 45 injured patients who

were admitted to the Gastroentrology Unit, Department of General

Surgery at Tanta University Hospital, between March, 1998 and February

2000. These patients were randomly classified into equal three groups:

Group {A}: Totally splenectomized group.

Group {B}: Splenectomy with intraperitoneal partial splenic autotransplantation group. Group {C}: Splenectomy with extraperitoneal partial •splenic

autotransplantation group.

All the patients were subjected to thorough history taking, physical examination and preoperative and postoperative investigations (one and three months) including: red blood cell counts, haemoglobin concentration, white blood cell counts, platelets count, pocked cell test, determination of Immunoglobulins IgM, IgA and IgG and abdominal ultrasonography with duplex scanning. The second part of this study was done on experimental animals.

The animals used in this study were 60 rabbits, which were housed in the central animal house in the period between March 1998 to February