EVALUATION OF THE ROLE OF HYPERBARIC OXYGEN THERAPY IN NON-ISCHEMIC DIABETIC FOOT LESION

Abstract

HBO is a non-invasive therapy. In its clinical applications, the patient breathes 100% while fully enclosed in a speciaLly designed chamber at ambient pressures up to three times normal atmospheric pressure. The primary effect of administering oxygen

at greater to dissolve

than normal atmospheric pressure is physically significant amounts of

oxygen at much increased the blood plasma. This

partial pressures in facilitates healing

through enhanced macrophage function,

fibroblast proliferation,

and collagen synthesis,

angiogenesis, and epithelization.

In addition HBO therapy improves leukocyte bacterial killing a't>ility for aerobic microorganisms and directly kills anaerobic microorganisms.