Management of Diabetes Mellitus in patient with decompensated liver disease

Abstract

Diabetes mellitus (DM) is considered to be one of the most common chronic diseases and a growing public health challenge globally, where an estimated 382 million people, corresponding to 8.3% of the world’s adult population, has diabetes. DM was found to be an important cause of liver disease, where patients with diabetes were found to have a spectrum of liver diseases, ranging from abnormal liver enzymes, nonalcoholic fatty liver disease (NAFLD), cirrhosis, hepatocellular carcinoma, and acute liver failure, all associated with the increased prevalence of hepatic complications including liver cirrhosis and portal hypertension. DM and insulin resistance are common in cirrhosis.The prevalence of diabetes is up to 30% in cirrhotic patients and prevalence increases with the severity of liver disease. Key words: Diabetes Mellitus in patient with decompensated liver disease.