Evaluation of myocardial injury in children with left-to-right shunt using a highly sensitive cardiac Troponin-I assay

Shaima mohsen abdelrahman;

Abstract


Summary
Congenital heart diseases are abnormalities of the heart and/or great vessels present at birth. They are not all that uncommon: 1% of live births have a congenital heart defect.
Left to right shunts are characterized by a "back-leak" of blood from the systemic to the pulmonary circulation.
Cardiac Troponin, especially cardiac Troponin-I (cTn-I), are the preferred biomarkers for the detection of cardiac injury.
International cardiology and laboratory medicine guidelines recommend hsTnI with excellent precision (<10%).
hsTnI is a cheap way that is capable of accurately and precisely detecting low levels of Troponin I enabling treatment and allowing earlier definitive diagnosis of acute myocardial injury than is currently possible.

The aim of this work was to evaluate the myocardial injury as detected by highly sensitive cardiac Troponin I (hsTnI) in children with left to right shunt.


Other data

Title Evaluation of myocardial injury in children with left-to-right shunt using a highly sensitive cardiac Troponin-I assay
Other Titles قياس نسبة التروبونين القلبي (اي) شديد الحســـــاسيه في الأطفال الذين لديهم عيوب خلقيه بالقلب تؤدي الى تدفق الدم من الجهه اليسرى إلى الجهه اليمنى
Authors Shaima mohsen abdelrahman
Issue Date 2012

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