Cerebral Venous Sinus Thrombosis in Pediatric age group Systematic Review
Aya Hussein Ibrahim Hussein;
Abstract
Cerebral venous sinus thrombosis (CVST) is an infrequent clinicopathological entity. The incidence of CVST in children and neonates has been reported to be as high as 0.76 per 100.000 child per year.
The predisposing factors to this condition are mainly genetic as well as and acquired prothrombotic states and infection.
The clinical picture of CVST is nonspecific, highly variable, and can mimic several other clinical conditions.
Diagnosis of CVST is established with the implementation of neuroimaging studies, especially MR imaging and venography.
Identification and elimination of the underlying cause, anticoagulation, proper management of intracranial hypertension and anticonvulsant prophylaxis constitute the cornerstones of CVST treatment.
Newer treatment strategies such as endovascular thrombolysis and decompressive craniectomy have been recently used in the treatment of CVST patients with variable success rates.
Further clinical research must be performed to delineate the exact role of these newer treatments in the management of severe cases of CVST. The recent advances in the diagnosis and treatment of patients with CVST have significantly lowered the associated mortality and morbidity and have improved the outcome of these patients.
The predisposing factors to this condition are mainly genetic as well as and acquired prothrombotic states and infection.
The clinical picture of CVST is nonspecific, highly variable, and can mimic several other clinical conditions.
Diagnosis of CVST is established with the implementation of neuroimaging studies, especially MR imaging and venography.
Identification and elimination of the underlying cause, anticoagulation, proper management of intracranial hypertension and anticonvulsant prophylaxis constitute the cornerstones of CVST treatment.
Newer treatment strategies such as endovascular thrombolysis and decompressive craniectomy have been recently used in the treatment of CVST patients with variable success rates.
Further clinical research must be performed to delineate the exact role of these newer treatments in the management of severe cases of CVST. The recent advances in the diagnosis and treatment of patients with CVST have significantly lowered the associated mortality and morbidity and have improved the outcome of these patients.
Other data
| Title | Cerebral Venous Sinus Thrombosis in Pediatric age group Systematic Review | Other Titles | الخثار فى الجيـوب الوريديـة الدماغيـة فى الأطفـــال | Authors | Aya Hussein Ibrahim Hussein | Issue Date | 2015 |
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