Sevoflurane Versus lsoflurane and Spinal Anesthesia during Elective Cesarean Birth
Diaa Eldin Aly Farghaly Sayed;
Abstract
Our hospital ethics committee approved this study, and written consent was obtained from all parturients. The study included 90 pregnant women required delivery by elective cesarean section in the department of Obstetrics and Gynecology, Assiut university Hospital between 2000 and
2002. Pregnant women were randomly assigned to recei,•e either sevoflurane, isoflurane or spinal anesthesia using an open (non-blinded) study design.
The general group of anesthesia was received rapid sequence induction using Thiopental (4-5 mg \kg) after 3 minutes of denitrogenation with I 00% 02• Cricoid pressure was applied and tracheal intubation was performed after muscle paralysis with Succinyl-choline ( 1.5 mg \ kg) IV. Anesthesia was maintained with either Isoflurane 0.5% end tidal Or Sevoflurane I% end tidal in combination with Nitrous oxide (N20) 50% in oxyge. Fresh gas flow was maintained at 3 L\minute until the time of delivery. Intraoperative analgesia was provided to all parturients with Fentanyl (1OOflg). Muscle relaxation was maintained \\ith atracurium I 0-
20 mg IV. as required.
The regional group received spinal block using 25-gauge spinal needle inserted at L2-3 or L3-4 interspace injecting 2-2.5 ml heavy bupivacaine with 0.5 mg morphine. Sensory level was determined using pinprick or ice to asses the maximal level.
2002. Pregnant women were randomly assigned to recei,•e either sevoflurane, isoflurane or spinal anesthesia using an open (non-blinded) study design.
The general group of anesthesia was received rapid sequence induction using Thiopental (4-5 mg \kg) after 3 minutes of denitrogenation with I 00% 02• Cricoid pressure was applied and tracheal intubation was performed after muscle paralysis with Succinyl-choline ( 1.5 mg \ kg) IV. Anesthesia was maintained with either Isoflurane 0.5% end tidal Or Sevoflurane I% end tidal in combination with Nitrous oxide (N20) 50% in oxyge. Fresh gas flow was maintained at 3 L\minute until the time of delivery. Intraoperative analgesia was provided to all parturients with Fentanyl (1OOflg). Muscle relaxation was maintained \\ith atracurium I 0-
20 mg IV. as required.
The regional group received spinal block using 25-gauge spinal needle inserted at L2-3 or L3-4 interspace injecting 2-2.5 ml heavy bupivacaine with 0.5 mg morphine. Sensory level was determined using pinprick or ice to asses the maximal level.
Other data
| Title | Sevoflurane Versus lsoflurane and Spinal Anesthesia during Elective Cesarean Birth | Other Titles | دراسة مقارنة التخدير باستخدام عقار السيفوفلوران بعقار الايزوفلوران أو التخدير النصفى للولادة القيصرية الإختيارية | Authors | Diaa Eldin Aly Farghaly Sayed | Issue Date | 2002 |
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