EAR, NOSE AND THROAT DISORDERS IN CHILDREN WITH DOWN SYNDROME

Abstract

Down syndrome IS the most autosomal aberration syndrome that was described by John Langdon Down in • 1866. (Nyhan, 1983) occurring in approximately I in 600

lin births in England and Wales. (Bain and Ellis, 1984).

lhL· incidence however Increases significantly with

c.H.Ivanc i ng maternal a.g._ e.

In women under 30. the

incidence IS about 0.6 in 1000 births; this increase to

• appro'\ i mately 20 111 1000 births for mothers aged 45 and on r. (Evans and Glass, 1976)

It is the one of the commonest congenital causes of severe mental retardation. (Elliot et al, 1981) In fact, 00\\'11 syndrome is the primary cause of retardation when the diagnosis is made af birth.