The use of different platelet concentrates in socket augmentation following tooth extraction (clinical and histomorphometric study)

Abstract

The aim of the present study was to compare between using PRGF and PRF in socket augmentation and their effect as a graft material and to find the role of the growth factor in bone regeneration and its effect on differentiation and maturation. Thirty subjects were included in this study. They were divided into three groups: group 1 included ten patients, their sockets augemented by PRGF after extraction, group 2 included ten patients their sockets augemented by PRF after extraction while group 3 included ten controls not received any augementation after extraction. Clinical parameters including; vertical bone height and bone width were recorded at baseline and at 8 weeks after extraction. Moreover, histomorphometric parameters including; total surface area, trabecular bone size and area fraction of newly formed bone were measured at 8 weeks after extraction by histomorphometric analysis. In the present study a core biopsy was taken after 8 weeks from tooth extraction which has undergone histomorphometric analysis, implant placement was also done at the same time.