A Retrospective Study of the Treatment Results & Patterns of Failure of Type II Endometrial Cancer Patients treated at Radiotherapy Department, NCI, Cairo University during the period from January 2000 till December 2012

Abstract

Aim of the study: To identify all clinico-pathological data, different treatment modalities and the different prognostic factors which affected the locoregional control (LC), disease-free survival (DFS), and overall survival (OS) of Type II endometrial cancer patients

Patients and methods: Data of Type II endometrial carcinoma patients who presented to the Radiation Oncology department, National Cancer Institute, Cairo University during the period from (2000-2012) were retrospectively reviewed .

Results and conclusions: Multivariate analysis identified stage as an independent prognostic factor for OS & DFS, and age was an independent prognostic factor for DFS and LC. Low pretreatment hemoglobin levels significantly affected OS.

Large and multicentric clinical trials are required to further study this group of patients and define optimum treatment modalities.

Keywords: Endometrial carcinoma, Radiotherapy, Chemotherapy