Retrospective Studv of Idiopathic Pulmonary Fibrosis Cases Presented to Chest Depanment in Cairo University in last 5 vears

Abstract

Background: IPF is defined as a specific form of chronic, progressive fibrosing interstitial pneumonia of unknown cause, occurring primarily in older adults, limited to the lungs, and associated with the histopathologic and/or radiologic pattern ofUIP. ' The pathologic processes that cause disease progression arc not well understood. The diagnosis of IPF requires multidisciplinary discussion between pu!monologists, radiologists, and pathologists experienced in the diagnosis of ILD. The disease course is highly variable and patients may be classified as "rapid" or "slow" progrcssors with a 5 year survival rate of only 20-30% following diagnosis.

Aim of the work: to review the cases of Idiopathic pulmonary fibrosis presented to chest department Cairo university Hospital during the last five years (2006-20 II).

Subjects and methods: The data was collected in this retrospective study from the available 90 files of idiopathic pulmonary fibrosis cases presented to chest department Cairo university Hospital during the last five years (2006-June 2011), statistics of idiopathic pulmonary fibrosis patients are done to detect risk factors, relation to smoking ,the way of diagnosis and the treatment given to them. Results: In the current study it was found that there is gradual increase in the incidence and prevelancc of cases of IPs in study period. Idiopathic pulmonary fibrosis has highest incidence among different subtypes of idiopathic interstitial pneumonia, there is annual increase in the incidence ofiPF cases. prevelance of!PF is more in females than males, non smokers than smokers, those with non­ occupational risk than those with occupational risk factor ,the mean age of presentation for IPF study population was 50 yr and the diagnosis of IPF by chest HRCT scan is more confident than lung biopsy.