Role of Radioactive 131ITherapy in Well Differentiated Thyroid Carcinoma
Hoda Fathy El Sayed;
Abstract
• Well differentiated thyroid carcinoma is the most common tumor of the thyroid gland, it's potentially curable disease. Patients are classified according to the risk stratification.
• Initial surgical treatment varied from hemithyroidectomy to near total thyroidectomy ± block neck dissection
• External neck irradiation with bulky local thyroid residual or with positive nodal involvement and in distant bone or brain metastatic disease.
• The patients are treated by radioiodine according to their risk stratification either by 30 mCi in low risk group and 80-100 mCi in high risk group, in metastatic patients according to the standard fixed dose we use up to 150 mCi for functioning tissue in the neck, 175 mCi for lymph node metastases and 200 mCi for metastases outside the neck.
• El-troxin is given as a replacement suppression therapy after 1311
therapy then stopped for 4 weeks before whole body scanning with 131I. the ablation may be repeated until complete ablation every 6 months. Therapy doses in metastatic patients repeated every 6-12 months until no uptake or 1 Ci is reached.
• Initial surgical treatment varied from hemithyroidectomy to near total thyroidectomy ± block neck dissection
• External neck irradiation with bulky local thyroid residual or with positive nodal involvement and in distant bone or brain metastatic disease.
• The patients are treated by radioiodine according to their risk stratification either by 30 mCi in low risk group and 80-100 mCi in high risk group, in metastatic patients according to the standard fixed dose we use up to 150 mCi for functioning tissue in the neck, 175 mCi for lymph node metastases and 200 mCi for metastases outside the neck.
• El-troxin is given as a replacement suppression therapy after 1311
therapy then stopped for 4 weeks before whole body scanning with 131I. the ablation may be repeated until complete ablation every 6 months. Therapy doses in metastatic patients repeated every 6-12 months until no uptake or 1 Ci is reached.
Other data
| Title | Role of Radioactive 131ITherapy in Well Differentiated Thyroid Carcinoma | Other Titles | دور اليود المشع في علاج سرطان الغدة الدرقية النوعي | Authors | Hoda Fathy El Sayed | Issue Date | 2005 |
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