The Role of Diffusion weighted Imaging versus dynamic multiphase contrast enhanced MRI in the evaluation of uterine malignancies

Abstract

Owing to its superior soft tissue delineation and multiplanar capability, MRI is considered the most accurate imaging modality for the evaluation of endometrial and cervical cancer, and is now an integral part of their local staging. The limitations of morphologic imaging especially in the presence of reported pitfalls such as loss of junctional zone definition, leiomyomas, overestimation of parametrial infiltration as well as bladder and rectal invasion has urged the need for modifying the standard imaging protocol used in endometrial carcinoma staging. Potential applications of fMRI include the challenging topics of distinguishing tumor from non-tumor tissue in cervical and endometrial cancer, pre-surgical mapping, and assessment of treatment response and prediction of treatment