Fetal middle cerebral artery/umbilical artery pulsatility index ratio for Prediction of Neonatal outcome among Women with Severe Preeclampsia

Abstract

In this study which included 100 women with severe preeclampsia admitted to Ain Shams Maternity University Hospital the aim was to evaluate the accuracy of middle cerebral/umbilical artery pulsatility index ratio in predicting admission to NICU, acidemia and low Apgar score at 5 minutes after birth in neonates of severe preeclamptic pregnant women. There was a positive significant correlation between MCA/UA PI ratio <1 and higher rates of NICU admission, 5 minutes Apgar score <7, but there was no significant differences between women who had a MCA to UA PI <1 and umbilical artery PH <7.2. The best cut off value of MCA/UA PI ratio for prediction of NICU admission was sensitivity 62.5%, specificity 71.43%, PPV 29.41%, NPP 90.91% and the accuracy 70%, the cut off value of MCA/UA PI ratio for prediction of low Apgar score at 5 min was sensitivity 50% and 88.10% specificity, estimated positive predictive value =44.44 and negative predictive value =90.24, and the cut off value of MCA/UA PI ratio for prediction of low UA PH was sensitivity 43.75%, specificity 69.05%, estimated positive predictive value =21.21, and negative predictive value =86.57.