Role of lectin like Oxidized LDL-1 Receptor and Hematological Changes of Acute Coronary Syndrome in Critically Ill Patients

Abstract

D eath from coronary artery disease is by far the leading cause of death worldwide. There is no doubt that a better understanding of atherothrombosis has guided development of improved diagnostic facilities as well as revascularization technologies in combination with current antithrombotic strategies that have altogether impressively reduced acute thromboembolic complications and death from cardiovascular causes within the last decades. However, the rate of ischemic complications even after optimal revascularization and medical therapy remains high. Similarly, morbidity and death associated with chronic ischemic heart disease and ischemic cardiomyopathy respectively are constantly rising. Therefore, there is still a strong need for effective primary prevention strategies, fast and accurate diagnostic procedures as well as for new and smart antithrombotic drugs. The review focuses on ACS which is one of the common problems we face in our career; intensive care medicine, appropriate early intervention in patients with ACS can save lives. This survival benefits, however, is time-dependant, and steadily declines in the hours that follow the first signs of ischemic injury. This is the famous time is muscle axiom that drives the early management of ACS, Worse prognostic information of ACS can be obtained from routine hematologic tests such as CBC through the important role of blood elements of the pathogenesis of ACS.