A Single Photon Emission computed Tomography Study in POSTCONCUSSIONAL SYNDROME

Abstract

Behavioral outcome after traumatic brain m.Jury reflects disturbance in the processing of internal and external stimulation, and disturbance of pre-existing physiological and psychological processes. Emotional distre'ss consistent with the accident and impairment adds to the credibility of patient complaints. There is an interaction between lesion effects and various emotional disturbances, which impacts employment, social relationships, and the enjoyment of life (Parker, 1996). The neuropsychiatric sequelae of minor head trauma have been the source of controversy. Most clinical and imaging studies have shown no alteration after concussion, but neuropsychological and neuropathological abnormalities have been reported (Drake eta/, 1996). SPECT appear to be more sensiti ve in detecting cerebral abnormalities after mild closed head injury, especially in patients with persistent postconcussive syndrome symptoms, than either CT or MRl (Kant et al, 1997). Single photon emission tomography SPECT is a brain imaging technique, which safely provides quantitative and regional measurement of cerebral blood flow, it is becoming increasingly available. It depends on the intravenous injection of gamma emitting radio labeled compounds, usually small lipophilic molecules that remain in place long enough to be monitored by a computer controlled rotating gamma camera. It provides a measure of regional cerebral blood flow, which is largely proportional to the rate of local metabolism. The advantage is that unlike PET, an expansive cyclotron is not required on site but it does not permit more elaborate metabolic sites (Bannister, 1992). Because of its capabilities, SPECT is well studied to the study of psychiatric disorders.