EXTRACELLULAR BIOSYNTHESIS OF SILVER NANOPARTICLES AND ITS ANTIMICROBIAL ACTIVITY

Abstract

Microbial synthesis of nanoparticles has a potential to develop, cost-effective and eco-friendly methods for the production of technology important materials. Silver nanoparticles have a great number of application, e.g. in non-linear optics, spectrally selective coating for solar energy absorption, biolabelling, intercalation materials for electrical batteries, high-sensitivity biomolecular detection and diagnostics, antimicrobials and therapeutics, catalysis and microelectronics. Nanoparticles resulting from some microbial processes have unique chemical and physical properties, different from the properties of conventionally nanoparticles, depending on microorganisms and medium used as well as operational conditions applied. The objective of this study is biosynthesis of the extracellular silver nanoparticles by some local strains through isolation and selection of isolates had the ability for AgNPs synthesis from different sources. Also, optimization of factors affecting silver nanoparticles biosynthesis using classical methods (one variable at a time) and the techniques of interaction between the factors through response surface methodology. Studies were focused on silver nanoparticles stability, characterization and its antimicrobial effects against various pathogens as well as some application.