HEPATIC RESECTIONS, 10 YEARS EXPERIENCE IN THE NATIONAL CANCER INSTITUTE, CAIRO UNIVERSITY

Abstract

Tumors of the liver represent one of the commonest malignancies worl wide, -of which hepatocellular carcinoma is the commonesr. Hepatocellular carcinoma is kno\vn to be a consequence of viral hepatitis HBV and HCV infections, hepato carcinogens e.g. Aflatoxi11 and chronic liver disease e.g. cirrhosis. genetic hemochromatosis and hereditary tyrosinemia. Abdominal pain and swelling are the commonest symptoms of HCC and hepatomegaly is the main physical sign in HCC. Diagnosis of HCC depends mainly on ultrasound or C.T examination of the liver, tumor marker study e.g. AFP and DCP and finally histologic diagnosis by guided needle cytology or biopsy. • Surgery remain the mainstay of treatment of HCC the results of hepatic resection v...as improved in the last 30 years because of the knowledge of the segmental anatomy of t_he liver and improved surgical techniques. The prognos[s of hepatocellular carcinoma is_ generally poor. However, the 5- year survival after liver resection varies between 25- 65%.