NON-STEROIDAL DRUGS USED IN MANAGEMENT OF MENOPAUSE
Mahmoud Yehia Nour-Eidin Mahmoud Sorour;
Abstract
Menopause is the permanent cessation of menses that occurs after the cessation of ovarian function , the climacteric is a phase in the aging process of women that marks the transition from the reproductive stage of life to the non reproductive stage and during which the ovarian function ceases.
Although menopause is a natural event , the years immediately before and the decades afterward are of much greater clinical significance , it can be uneventful or a time of significant symptoms.
Menopause occurs at a median age of 51 years, the age of menopause appears to be determined genetically and does not seem to be related to race, nutritional status, age of menarche however it may occur earlier in cigarette smokers.
The main mechanism underlying the menopause is the depletion of the store of primordial follicle, another mechanism, however could be involved, namely loss of follicular responsiveness to the pituitary gonadotropins, this is supported by the presence of residual, dormant primordial follicles in postmenopausal ovaries and a significant increase in serum follicular stimulatimg hormone (FSH) concentration with distinct concomitant decrease in estradiol (E2) level.
Although menopause is a natural event , the years immediately before and the decades afterward are of much greater clinical significance , it can be uneventful or a time of significant symptoms.
Menopause occurs at a median age of 51 years, the age of menopause appears to be determined genetically and does not seem to be related to race, nutritional status, age of menarche however it may occur earlier in cigarette smokers.
The main mechanism underlying the menopause is the depletion of the store of primordial follicle, another mechanism, however could be involved, namely loss of follicular responsiveness to the pituitary gonadotropins, this is supported by the presence of residual, dormant primordial follicles in postmenopausal ovaries and a significant increase in serum follicular stimulatimg hormone (FSH) concentration with distinct concomitant decrease in estradiol (E2) level.
Other data
| Title | NON-STEROIDAL DRUGS USED IN MANAGEMENT OF MENOPAUSE | Other Titles | العقاقير غير الستيرويدية المستخدمة فى معالجة سن اليأس | Authors | Mahmoud Yehia Nour-Eidin Mahmoud Sorour | Issue Date | 2002 |
Recommend this item
Similar Items from Core Recommender Database
Items in Ain Shams Scholar are protected by copyright, with all rights reserved, unless otherwise indicated.